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ABOUT THE MEETING

The NVHG organizes an annual meeting where prominent researchers in the field of Human Genetics are invited to present their recent work and part of the program is enriched by our sister associations, the VKGN, VKGL and the NACCG. 

In the meeting, both fundamental and more clinically applied topics alternate encouraging a research-stimulating character.

The annual General Members Meeting of the NVHG is also held during this event.

We are pleased to confirm that the NVHG Virtual Conference will be held on:

17  September 2021

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WELCOME

Dear colleague,

Welcome to the 2021 annual meeting of the Dutch Society of Human Genetics.

Exactly one year ago we thought that our successful first virtual meeting would be a “one-of-a-kind interesting experience”, but unfortunately also this year, we will have to go virtual. However, by now everyone is highly experienced in attending virtual symposia, interacting via chats and staring at a screen for a whole day.

We have composed a diverse (interactive) program focusing on the newest developments in the genetics field with frequent breaks to stretch the legs en interact with the sponsors and potential new collaborators.

We will kick of our meeting with the Sandkuijl lecture. From a historical perspective, every two years, the NVHG selected an outstanding researcher with a proven and substantial track record in the same field of genetics as Lodewijk Sandkuijl to award this prestigious personal prize. From this year onwards, we will honor the philosophy of this award but will select a young talent who contribute significant to the development of methodology in the field of bioinformatics and/or statistical genetics. We are pleased to announce that the Lodewijk Sandkuijl Lecture 2021 will be awarded to Michel Nivard for his excellent work in statistical genetics of complex disorders.

Since translational genetic research is the focus of today’s program we have invited Annemieke Aartsma-Rus, Willeke van Roon-Mom and Clara van Karnebeek to update you on national initiatives for therapy development in rare diseases.
Guillaume Canaud, Tjitske Kleefstra and Erica van den Akker will share their experiences with therapeutic trials.
Ruben Kok, Joyce van Meurs and Terry Vrijenhoek will take you on their journey through the field of (inter)national genome initiatives focusing on the collaborative landscapes for optimized disease diagnosis, therapeutics and prevention. We invite you to participate in the round table discussions by using the chat box.

We have received high quality abstracts for our Hot & Happening session in the afternoon and excellent nominees for the NVHG Young Investigator Award that will be presented in the afternoon session.
We will finish the conference with the keynote lecture of Louis Vermeulen, who will present his exciting new work, recently published in Nature, on the competitive behavior of colorectal cancer stem cells, and the possibilities this may give for preventive therapy.

I would like to thank the sponsors for their essential and generous financial contribution to this meeting. Please contact and meet them during the breaks.

I wish you a very inspiring meeting with many new ideas and opportunities for future collaborations!

Mieke van Haelst

Mieke van Haelst
President

LODEWIJK SANDKUIJL

DR. MICHEL NIVARD

The winner of the Lodewijk Sandkuijl award 2021 is Dr. Michel Nivard, VU University Amsterdam. He will receive this prize during the NVHG Annual Meeting on Friday 17 September, and will give an overview of the research he is conducting. Interested? Register now for the NVHG Annual Meeting 2021.

SPEAKERS

PROGRAMME

*This is preliminary programme (version 07 Sep 2021)

FRIDAY 17 SEPTEMBER

 

09:00     

Walk-in – take own coffee, look around, solve technical issues

09:30    

Welcome and opening

 

Mieke van Haelst & Terry Vrijenhoek

09:40    

Sandkuyl Lecture

 

– Genetics delivers high precision science & medicine; can we also deliver unbiased science & medicine?

 

Dr. Michel Nivard, Amsterdam UMC

 

 

10:20     

Mini-break

10:30     

Session 1: National initiatives for therapy development in rare diseases

 

– Dutch Centre for RNA therapeutics

 

Prof. dr. Aartsma-Rus, LUMC

 

Prof. dr. W. van Roon-Mom, LUMC

 

– ‘N-of-one’ for all

 

Prof. dr. C. van Karnebeek, Radboudumc

 

– Round Table discussion

  

 

11:15     

Mini-break

11:20     

Session 2: Experiences with rare disease therapeutic trials

  

– Targeted therapy in patients with PIK3CA related overgrowth syndromes

 

Prof. dr. G. Canaud, Université de Paris, France

  

– Clinical effect studies in Kleefstra syndrome

 

Prof. dr. T. Kleefstra, Radboudumc

  

– Therapeutic opportunities for obesitas

 

Dr. E. van den Akker, Amsterdam UMC

  

–  Round table discussion

  

12:20     

Lunch break

  

13:00

Session 3: Current genome initiatives: regional, national, European

  

–  Beyond 1+ Million Genomes

 

Dr. R. Kok, Dutch Techcentre for Life Science

  

– GOALL study

 

Prof. J. van Meurs, Erasmus MC

  

– HUGE-NL

 

Dr. T. Vrijenhoek, UMCU

  

–  Round table discussion

  

13:55     

Mini-break

14:05

Young Investigator Award

  

14:15     

Session 4: Hot & Happening

 

– Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman Syndrome mouse model

 

Claudia Milazzo, Erasmus MC

 

– Inherited variants in CHD3 demonstrate variable expressivity in Snijders Blok-Campeau syndrome

 

Jet van der Spek, Radboudumc

 

– Reduced MUNC18-1 levels, synaptic proteome changes and altered network activity in iPSC-derived neurons from six STXBP1-Syndrome patients

 

Annemiek van Berkel, Amsterdam UMC- locatie VU

 

– Identification of enhancer regions to expose novel genetic causes of spinocerebellar ataxia

 

Fatemeh Ghorbani, UMC Groningen

  

15:05     

Mini-break

15:15    

Session 5: Keynote Lecture 

 

– Outcompeting cancer by personalized chemoprevention

 

PhD. Louis Vermeulen, Amsterdam UMC

  

 

16:00

Closure

  

Mieke van Haelst & Terry Vrijenhoek

16:10   

NVHG Algemene ledenvergadering (ALV)

 

Aansluitend: uitreiking puzzelprijs

 

09:00     

Walk-in – take own coffee, look around, solve technical issues

09:30    

Welcome and opening

 

Mieke van Haelst & Terry Vrijenhoek

09:40    

Sandkuyl Lecture

 

– Genetics delivers high precision science & medicine; can we also deliver unbiased science & medicine?

 

Dr. Michel Nivard, Amsterdam UMC

 

 

10:20     

Mini-break

10:30     

Session 1: National initiatives for therapy development in rare diseases

 

– Dutch Centre for RNA therapeutics

 

Prof. dr. Aartsma-Rus, LUMC

 

Dr. W. van Roon-Mom, LUMC

 

– ‘N-of-one’ for all

  

Prof. dr. C. van Karnebeek, Radboudumc

  

– Round Table discussion

  

11:15     

Mini-break

11:20     

Session 2: Experiences with rare disease therapeutic trials

  

– Targeted therapy in patients with PIK3CA related overgrowth syndromes

 

Prof. dr. G. Canaud, Université de Paris, France

  

– Clinical effect studies in Kleefstra syndrome

 

Prof. dr. T. Kleefstra, Radboudumc

  

– Therapeutic opportunities for obesitas

 

Dr. E. van den Akker, Amsterdam UMC

  

–  Round table discussion

  

12:20     

Lunch break

  

13:00

Session 3: Current genome initiatives: regional, national, European

  

–  Beyond 1+ Million Genomes

 

Dr. R. Kok, Dutch Techcentre for Life Science

  

– GOALL study

 

Prof. J. van Meurs, Erasmus MC

  

– HUGE-NL

 

Dr. T. Vrijenhoek, UMCU

  

–  Round table discussion

  

13:55     

Mini-break

14:05

Young Investigator Award

  

14:15     

Session 4: Hot & Happening

 

– Antisense oligonucleotide treatment rescues UBE3A expression and multiple phenotypes of an Angelman Syndrome mouse model

 

Claudia Milazzo, Erasmus MC

 

– Inherited variants in CHD3 demonstrate variable expressivity in Snijders Blok-Campeau syndrome

 

Jet van der Spek, Radboudumc

 

– Reduced MUNC18-1 levels, synaptic proteome changes and altered network activity in iPSC-derived neurons from six STXBP1-Syndrome patients

 

Annemiek van Berkel, Amsterdam UMC- locatie VU

 

– Identification of enhancer regions to expose novel genetic causes of spinocerebellar ataxia

 

Fatemeh Ghorbani, UMC Groningen

  

15:05     

Mini-break

15:15    

Session 5: Keynote Lecture 

 

– Outcompeting cancer by personalized chemoprevention

 

PhD. Louis Vermeulen, Amsterdam UMC

  

 

16:00

Closure

  

Mieke van Haelst & Terry Vrijenhoek

16:10   

NVHG Algemene ledenvergadering (ALV)

 

Aansluitend: uitreiking puzzelprijs

SPONSORS

We express our gratitude to all our sponsors for their continued support.

GENERAL INFORMATION

REGISTRATION INFORMATION

Registration for the Meeting is OPEN!
When registering for the conference, you will have to agree to the General Terms & Conditions for participants.

NVHG collects and uses your personal information to:

–          facilitate registration for the event
–          send you a confirmation e-mail
–          send you a personal link to participate in the event
–          send you a survey after the event
–          show your name in the online platform
–          collect viewing statistics

Your data will be shared with Invitado, our online event platform partner, to create personal login credentials.
Invitado will deleted these data within 30 days after the event.

One fee for all participants

50
  • All live sessions
  • On-demand sessions

CANCELLATIONS AND REFUNDS

 

Notice of cancellation must be made in writing by e-mail to the Meeting organisers:  henny.schurmann@mumc.nl

Registration fees may be refunded if written cancellation has been received as follows:

  • until Sep 10, 2020: full refund
  • from Sep 11, 2020: 50% refund

The cancellation will not be effective until a written acknowledgement from the NVHG organisers is received. In the case of over-payment or double payment, refund requests must be made in writing and sent to the meeting organisers by e-mail. No refunds will be granted for unattended events or early termination of attendance, in case of cancellation of speakers or any other incidents during the conference, which are beyond the control of the conference organisers.

No exceptions to the refund policy can be made, including health or family issues. By registering to the NVHG Annual Meeting 2020, participants agree that the organising committee does not assume any liability whatsoever.

 

ACCESS TO THE VIRTUAL PLATFORM

Participants will receive by email the instructions to access the platform once registered.

CERTIFICATES

Certificates of attendance will be sent to all participants electronically after the meeting when attendance is confirmed in the online platform.

ACCREDITATION

Accreditation will be given only when participants request it at the registration and when the attendance is confirmed by logging in to the meeting. 
BIG number and full name should be provided at registration.

LANGUAGE

The official language of the meeting will be English. No simultaneous translation will be provided.